Opencore to run two Mac computers by one external drive.

Hi, I'm not sure if its possible to perform one external macOS drive to boot two computers.

I have MacPro 5.1 with OpenCore'd Sequoia macOS and MacBook Pro 2020 (intel i9)

I would like to use the same external drive to run installed macOS on unsupported MacPro and alternately use the same drive to run the samemacOS on natively suported MacBookPro.

Is it possible?

Many years ago such a disk with the operating system allowed me to run any mac computer on intel, but today I see that it is more complicated. I will be grateful for any help and answer.