Ready to install first Hackintosh but two questions first about BIOS and SSD+HDD

Hey guys,

I just prepared the bootable USB using the vanilla method and I'm ready to give my first try creating a Hackintosh.

Question: Do I have to do something on the BIOS before installing it? I saw a few different tutorials on youtube and a few of them made a few changes on the BIOS config before installing macos.

Do I have to do something? Couldn't find anything related on the matter in the FAQ or in the Vanilla method tutorial page.

Also, I have an SSD and an HDD in this machine. I'm going to install macos on the SSD, but do I have to wipe out both before the installation? (right after you boot with the USB for the first time) or should I just erase the SSD and the HDD is going to work fine?

Here is my setup:

CPU: i7 7700 3.50GHz Skylake

Cpu Cooling: Cooler Master Seidon 120 Ver.2

Motherboards: Gigabyte B250-HD3P - Intel KabyLake ATX

Memory (RAM): Corsair Vengeance LPX 16GB (2x8GB) 3000MHz DDR4 Memory

Hard Drive (HDD): 1TB Seagate Barracuda Hard Drive 3.5 SATA III

Solid State Drive (SSD): 240GB Kingston HyperX Fury Solid State Drive

Graphics Card (GPU): Geforce GTX 1060 3GB

Power Supply (PSU): 500W Aerocool Integrator 80

Wi-Fi Card: TP Link 300Mbps Wireless N PCI

Thanks